Pressure ulcers often occur in long-term bedridden patients, not only affect the treatment process, but also threaten the patient's life and health. Sanshi Shengxin ointment is a hospital preparation of Anhui Provincial Acupuncture Hospital. Its theory comes from the "Experience Collection of Selection Science", which has the effect of reducing swelling and relieving pain, removing saprophytic muscle and so on. To explore the principle of Sanshi Shengxin ointment in the treatment of pressure ulcers can provide a theoretical basis for clinical treatment and research, and promote new treatment methods and options.