基于数据挖掘的中药治疗血管性痴呆的组方用药规律分析
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1.河南中医药大学;2.河南省中医院

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河南省中医药科学研究重大专项课题(20-21ZYZD09);河南省中医临床学科领军人才培育计划项目 (201301006);河南省中医药科学研究专项课题 (2019ZY2003、20-21ZY2204);中医药古籍和特色技术传承专项(0686-204001171345N);加强中医药科技成果转化研究(GZY-KJS-2020-006)。 ]


Data Mining-based Analysis of Prescription and Medication Rules of Traditional Chinese Medicine for Restless Leg Syndrome
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    摘要:

    目的:借助中医传承辅助平台(V2.5),对中国知网(CNKI)、中国生物医学文献数据库(CBM)、维普数据库(VIP)和万方数据库中运用中医药治疗血管性痴呆的方剂进行检索归纳并分析其组方用药规律。方法:检索相关数据库从建库到2020年1月以中医药治疗血管性痴呆的文献,运用中医传承辅助平台系统,进行相关数据的挖掘分析。结果:共筛选出符合要求的198首方剂,涉及171味中药,挖掘出处方中药物的性味归经、用药频次、组方规律、药物关联度,演化得出核心组合20个、新处方9个,为中医药临床治疗痴呆提供新的参考。

    Abstract:

    Objective: With the aid of the traditional Chinese medicine inheritance assistant platform (V2.5), to search and summarize the prescriptions for the treatment of vascular dementia with traditional Chinese medicine from CNKI, CBM, VIP and Wanfang database, and analyze the medication rules of the prescriptions.METHODS: Literature on the treatment of vascular dementia with traditional Chinese medicine was retrieved from the relevant database from its establishment to January 2020, and relevant data were mined and analyzed by using the TCM inheritance assistant platform system.RESULTS: A total of 198 prescriptions that met the requirements were screened out, involving 171 traditional Chinese medicines. The nature and taste of the drugs in the prescriptions, the frequency of medication, the rule of formulation and the drug correlation degree were found out, and 20 core combinations and 9 new prescriptions were obtained through evolution, which provided new reference for the clinical treatment of dementia with traditional Chinese medicine.

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  • 收稿日期:2021-11-04
  • 最后修改日期:2021-11-04
  • 录用日期:2021-11-29
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