降尿酸是治疗痛风和高尿酸血症的基本方法，目前降尿酸作用途径主要是通过抑制黄嘌呤氧化酶、腺苷脱氨酶等合成酶的活性，或（且）影响肾脏尿酸转运蛋白（OAT1、OAT3、URAT1、GLUT9）等的表达，进而降低尿酸的水平。由于中药治疗高尿酸血症及痛风的作用机制尚不明朗，因此本文通过检索中国知网、维普、万方、pubMed、Embase等数据库，筛选了具有降尿酸单味中药的相关文献，总结了具有降尿酸及明确作用机制的单味中药，并进行功效归类，有助于以后研究者及临床医师对其作用机制的进一步研究，为防治痛风和高尿酸血症提供更可靠更安全的中医治疗依据。

Abstract: Lowering uric acid is the basic method for the treatment of gout and hyperuricemia. The current way of lowering uric acid is mainly through inhibiting the activity of xanthine oxidase, adenosine deaminase and other synthase enzymes, or (and) affecting the renal uric acid transporter (OAT1, OAT3, URAT1, GLUT9) and other expressions, thereby reducing the level of uric acid. Since the mechanism of action of traditional Chinese medicines in the treatment of hyperuricemia and gout is still unclear, this article searches the Chinese National Knowledge Base, Weipu, Wanfang, pubMed, Embase and other databases to screen the relevant literatures with single Chinese medicine for lowering uric acid, and summarize A single Chinese medicine for lowering uric acid and a clear mechanism of action, and classifying its efficacy, will help researchers and clinicians to further study its mechanism of action in the future, and provide more reliable and safe Chinese medicine treatment for the prevention and treatment of gout and hyperuricemia in accordance with.

国家中医药管理局第四批全国中医（临床、基础）优秀人才研修项目【国中医药人教发（2017）24号】