完带汤化裁联合西药治疗复发性外阴阴道假丝酵母菌病的Meta分析
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厦门市中医院(福建 厦门 361000)

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Meta-analysis of Wandai Decoction combined with western medicine for Recurrent vulvovaginal candidiasis
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    摘要:

    目的 系统评价完带汤化裁联合西药治疗复发性外阴阴道假丝酵母菌病(recurrent vulvovaginal candidiasis,RVVC)的有效性和安全性。方法 检索CNKI、Sinomed、WanFang、VIP、PubMed、Embase、Cochrane Library等数据库,筛选完带汤化裁联合西药治疗RVVC的临床随机对照研究,用RevMan5.3软件进行数据分析。结果 共纳入10个研究,病例1075例。Meta分析结果显示:完带汤化裁联合西药治疗RVVC有效率高于单纯西药,且可降低复发率,改善阴道微生态,两组比较有统计学差异。结论 完带汤化裁联合西药治疗RVVC具有良好效果。

    Abstract:

    Objective:To systematically evaluate the efficacy and safety of Wandai Decoction with western medicine in the treatment for recurrent vulvovaginal candidiasis(RVVC). Methods:CNKI, Sinomed, WanFang, VIP, PubMed, Cochrane Library, and EMbase were searched from the database establishment to December 2019 to collect the randomized controlled trials(RCT) about the treatment of RVVC with Wandai Decoction combined with western medicine, and the data were analyzed by RevMan 5.3 software. Results:10 studies were included and the total sample size was 1075 cases. Meta analysis results demonstrated that in the total clinical effective rate,Wandai Decoction with western medicine was superior to western medicine. In addition, Wandai Decoction with western medicine was better than western medicine in terms of reducing recurrence rate and improving vaginal microecology. Conclusion:Wandai Decoction with western medicine has superior efficacy in the treatment for RVVC, and this conclusion still needs to adopt well-designed large-sample RCT to verify its reliability.

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梁玉燕,陈锦红,吴涢婷,曾丽雪.完带汤化裁联合西药治疗复发性外阴阴道假丝酵母菌病的Meta分析[J].,2021,20(4):53-57

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历史
  • 收稿日期:2020-09-21
  • 最后修改日期:2020-10-19
  • 录用日期:2020-12-01
  • 在线发布日期: 2021-09-03
  • 出版日期: 2021-08-25