基于络病理论运用中药保留灌肠法治疗多囊卵巢综合征临床观察
作者单位:

苏州市中医医院

基金项目:

※基金项目 江苏省科技厅重点研发计划(社会发展)项目(No.BE2017662);江苏省中医药科技发展计划项目(No.ZD201908);苏州市科技发展计划[民生科技-医疗卫生应用基础研究(第二批)]项目(No.SYSD2019159)


Discussion on pathogenesis of PCOS based on collateral disease theory and treatment of retention enema with traditional Chinese Medicine
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    摘要:

    目的 通过检测多囊卵巢综合征(PCOS)患者子宫螺旋动脉、卵巢间质动脉的血流动力学参数及中药保留灌肠治疗后的改善情况,结合其它影像学、实验室指标,探讨PCOS与中医络病的相关性。方法 (1)将30例PCOS患者作为观察组,30例正常体检者作为对照组,于刚入组时检测子宫螺旋动脉、卵巢间质动脉的血流动力学参数(RI、S/D),两组间进行比较;(2)比较30例PCOS患者中药保留灌肠治疗前后的子宫螺旋动脉、卵巢间质动脉的血流动力学参数(RI、S/D)、窦卵泡数量、卵巢体积、血清睾酮、性激素结合球蛋白(SHBG)水平。结果 观察组治疗前的子宫螺旋动脉血流动力学参数(RI、S/D)均高于对照组,卵巢间质动脉血流动力学参数(RI、S/D)均低于对照组,差异有统计学意义(P<0.05)。观察组治疗后与治疗前比较,子宫螺旋动脉RI、S/D下降,卵巢间质动脉RI、S/D上升,窦卵泡数减少,卵巢体积减小,睾酮下降,差异均具有统计学意义(P<0.05)。结论 通过检测数据可推论PCOS属中医络病范畴,中药保留灌肠通过疏通局部络脉可改善卵巢、子宫的病态血流状态及其它重要指标。

    Abstract:

    Objective: To explore the correlation between PCOS and collateral disease of traditional Chinese medicine by detecting the hemodynamic parameters of uterine spiral artery and ovarian stromal artery in patients with polycystic ovary syndrome (PCOS). Methods: 1 The hemodynamic parameters (RI, S / D) of uterine spiral artery and ovarian stromal artery in 22 patients with PCOS were compared with that of 22 patients with routine physical examination; 2. The hemodynamic parameters (RI, S / D), antral follicle number, ovarian volume, blood testosterone (T) and sex hormone binding globulin of 22 PCOS patients before and after TCM retention enema treatment were compared (SHBG) level. Results: the hemodynamic parameters RI and S / D of uterine spiral artery in PCOS group were higher than those in control group, the difference was statistically significant (P < 0.05); while the hemodynamic parameters RI and S / D of ovarian stromal artery in PCOS group were lower than those in control group (P < 0.05). Compared with before treatment, RI and S / D of uterine spiral artery decreased, RI and S / D of ovarian stromal artery increased, antral follicle number decreased, ovarian volume decreased, testosterone (T) decreased in PCOS group compared with before treatment (P < 0.05). Conclusion: PCOS belongs to the category of collateral disease of traditional Chinese medicine according to the test data of Western medicine. TCM retention enema can improve the morbid blood flow state of ovary and uterus and other important indicators by dredging local collaterals, which is worthy of clinical promotion.

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杨荣仙,王艳清.基于络病理论运用中药保留灌肠法治疗多囊卵巢综合征临床观察[J].,2020,19(6):54-57

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  • 收稿日期:2020-07-25
  • 最后修改日期:2021-01-29
  • 录用日期:2020-09-08
  • 在线发布日期: 2021-07-09
  • 出版日期: 2020-12-25